Bioorganic chemistry is chemistry at the interface of organic and biological chemistry and involves the design, synthesis and evaluation of substrates, probes, and materials for the study of biological systems and principles. Bioorganic chemistry can also take inspiration from biology for the design and synthesis of novel molecules and materials for non-biological applications. Liviu Mirica is involved with the development of bifunctional compounds for controlling beta-amyloid peptide aggregation and inhibitors for histone demethylase enzymes. Kevin Moeller's group is developing electrochemical arrays for the study of protein receptor substrate interactions. Jay Ponder’s group is involved in developing computational tools for studying peptide and protein folding and for the modeling of ligand-receptor binding. John Taylor’s group is studying DNA photodamage and developing nucleic acid-based systems for probe and drug activation and nanoparticle assembly.