Engines Through the Ages - Thursday, October 4th, 2018 - 4:00 pm

Life After a Nobel Prize - Friday, October 5th, 2018 - 11:00 am

Amidine-based catalysts developed by the Birman group show remarkable efficacy and versatility in promoting enantioselective acylation reactions and related transformations. The highly effective kinetic resolution of racemic β-lactam derivatives shown here was achieved by Valentina Bumbu via methanolysis in the presence of (S)-benzotetramisole (BTM).  The resulting enantioenriched protected β-aminoacids may find applications in designing peptidomimetics.

Using a pulsed laser, the Michael Gross group photolyzes HO-OH to produce HO• for foot printing solvent-accessible side chains on proteins. The approach, coupled with MS analysis, maps protein interfaces faster than a protein can unfold.

Three synthetic bacteriochlorins (mauve, gold, teal) are each attached to a native-like bacterial photosynthetic β-peptide (green), which self assembles with α-peptide (blue) and bacteriochlorophyll (purple) to form a dyad (top left) and then a cyclic oligomer with enhanced absorption (lower left).  The three constructs can be combined to give cyclic oligomers (top right) with blended bacteriochlorin absorption (lower right) and ~95% energy-transfer efficiency.

The image shows a "site-selective" Wacker oxidation on a microelectrode array, fabricated(?) by Kevin Moeller's research group. In this experiment, the Wacker oxidation is triggered by using the electrodes in the array to generate a Pd(II) oxidant.

The Hayes and Conradi groups are collaborating on in situ high-pressure high-temperature NMR to monitor the reaction of CO2 as it converts to magnesium carbonate and calcium carbonate.  This work involves WU's Consortium for Clean Coal Utilization

Read more in this special issue of Environmental Science & Technology: Surface et al. Environ. Sci. Technol., 2013, 47, 119?125. DOI: 10.1021/es301287n

The photosynthetic megacomplex from a cyanobacterium, which scientists have managed to isolate in its complete, functioning form, weighs about 6 million Daltons. Bob Blankenship and Michael Gross collaborated on the research.

Azapentadienyl-metal complexes possess two potential sites of reactivity for electrophiles, the nitrogen atom and the basic metal center.  The Bleeke group has investigated the reactions of (1,2,3-η3)-(5-t-butylazapentadienyl)Rh(PMe3)x (x = 2 or 3) and (1,2,3-η3)-(5-t-butylazapentadienyl)Ir(PEt3)x (x = 2 or 3) with triflic acid and has shown that either the nitrogen atom or the metal center can serve as the primary reaction site (see accompanying graphic).

Seminars

Date Event description Operations
Sep
20
New Strategies for the Catalytic Enantioselective Synthesis of Chiral Amines and Other Challenging Scaffolds | Steven Malcomson - Duke University
@ 4:00 pm
Sep
27
All Else Being Equal: Hierarchical Structure in Electrochemical Materials | Robert Coridan - University of Arkansas
McMillen 311 @ 4:00 pm
Oct
04
Engines Through the Ages | Fraser Stoddart - Northwestern University
Graham Memorial Chapel - Weissman Lecture @ 4:00 pm