Skip to main content
  • Arts & Sciences
  • Washington University in St. Louis

Search form

Home

Department of Chemistry

Main Menu

  • Faculty & Staff
  • Graduate
  • Undergraduate
  • Resources
  • Research
  • Events
  • Course Pages
  • Calendar

You are here

Home / Faculty & Staff / Jonathan Barnes

Jonathan Barnes

Jonathan Barnes

Assistant Professor, Department of Chemistry
Degrees: 
Postdoctoral Fellow, Massachusetts Institute of Technology
Ph.D. Northwestern University
B.S. M.S. University of Kentucky
E-mail: 
jcbarnes@wustl.edu
Phone: 
314-935-7921
Office: 
Bryan Hall 413A
Website: 
http://jbarnes.wustl.edu

Barnes Integrated Materials Research Group

Research Areas

Synthetic Organic Chemistry / Polymer Synthesis / Supramolecular Chemistry / Nanomaterials / Biomedical Engineering / Inorganic & Environmental Chemistry

 

Research Interests

The Barnes Integrated Materials Chemistry Research Group employs a multi-disciplinary approach towards research challenges in the areas of stimuli-responsive materials, combination therapeutics, templated biomaterials, and porous crystalline materials that serve as a platform for catalysis, chemical separation, and energy storage applications.  The “keystone” of our research program is synthetic organic chemistry, which is central to the preparation of all functional materials in our group.  Supramolecular and polymer chemistries are directly associated with this keystone, and together, all three areas represent the foundation of the research group.  We aim to build on this foundation by constructing novel 'smart' materials with well-defined functions – for both fundamental and applied purposes – that will ultimately lead us down research pathways in the areas of nanomaterials, biomedical engineering, and inorganic and environmental chemistries. 

Researchers who join the Barnes laboratory will gain valuable experience in a broad range of areas and techniques, such as synthetic chemistry, spectrometric identification of organic compounds, polymer synthesis, characterization of non-covalent bonding interactions and host-guest systems, absorption spectroscopy, electrochemistry, size-exclusion chromatography, dynamic light scattering, cell culturing, and in vivo efficacy studies.  The new Barnes group research space will consist of a large synthesis laboratory (multiple fume hoods, glovebox, solvent purification system, etc.), in addition to a biological laboratory (complete with a cell culture room) and an instrument room for compound purification, polymer analysis, electrochemistry, and optical absorption spectroscopy experiments.

 

Appointments

July 2016-present, Assistant Professor, Department of Chemistry, Washington University in St. Louis

 

Awards and Fellowships

2017 Young Investigator Award (Cancer Research Foundation) November 2017

 

2017 Packard Fellowship for Science and Engineering (Packard Foundation) October 2017

 

2017 Foresight Fellow - Synthetic Polymer Chemistry (Foresight Institute) March 2017

2015 IUPAC-SOLVAY International Award for Young Chemists April 2015 

Northwestern Department of Chemistry Award for Excellence in Graduate Research March 2015 

Howard Hughes Medical Institute Postdoctoral Fellow of the Life Sciences Research Foundation August 2014 

2013 Foresight Institute Distinguished Student Award Winner February 2014 

Department of Energy Innovations in Fuel Cycle Research Award June 2013 

Department of Energy Travel Award to Attend ISMSC-8 (July 2013) May 2013

Northwestern International Institute for Nanotechnology Ryan Fellowship July 2012 

Department of Defense National Defense Science & Engineering Graduate Fellowship April 2012 

World Class University Fellowship – NanoCentury KAIST Institute / Korea September 2011 

Thomas B. Nantz Memorial Scholarship (Excellence in Chemistry), University of Kentucky August 2001

 

Selected Publications (30+ total)

Greene, A. F.; Danielson, M.; Liles, K. P.; Delawder, A. O.; Li, X.; Natraj, A.; Wellen, A.; Barnes, J. C.* Redox-responsive Artificial Molecular Muscles: Reversible Radical-based Self-assembly for Actuating Hydrogels. Chem. Mater. 2017, 29, 9498–9508.

Barnes, J. C.; Bruno, P.; Nguyen, H. V.-T.; Liao, L.; Liu, J.; Hemann, M. T.; Johnson, J. A. Using an RNAi Signature Assay to Guide the Design of Three-Drug Conjugated Nanoparticles with Validated Mechanisms, In Vivo Efficacy, and Low Toxicity. J. Am. Chem. Soc. 2016, 138, 12494–12501.  Highlighted in MIT News

Barnes, J. C.; Ehrlich, D. J.; Gao, A. X.; Leibfarth, F. A.; Jiang, Y.; Zhou, E.; Jamison, T. F.; Johnson, J. A. Iterative Exponential Growth of Stereo- and Sequence-Controlled Polymers. Nature Chem. 2015, 7, 810–815. Highlighted in RSC’s Chemistry World.

Barnes, J. C.; Dale, E. J.; Prokofjevs, A.; Narayanan, A.; Gibbs-Hall, I. C.; Juríček, M.; Stern, C. L.; Sarjeant, A. A.; Botros, Y. Y.; Stupp, S. I.; Stoddart, J. F. Semiconducting Single Crystals Comprising Segregated Arrays of Complexes of C60. J. Am. Chem. Soc. 2015, 137, 2392–2399.

Barnes, J. C.; Frasconi, M.; Young, R. M.; Khdary, N. H.; Liu, W.-G.; Dyar, S. M.; McGonigal, P. R.; Gibbs-Hall, I. C.; Diercks, C. S.; Sarjeant, A. A.; Stern, C. L.; Goddard, W. A., III; Wasielewski, M. R.; Stoddart, J. F. Solid-State Characterization and Photoinduced Intramolecular Electron Transfer in a Nanoconfined Octacationic Homo[2]Catenane.  J. Am. Chem. Soc. 2014, 136, 10569‒10572.

Juríček, M.; Strutt, N. L.; Barnes, J. C.; Butterfield, A. M.; Dale, E. J.; Baldridge, K. K.; Stoddart, J. F.; Siegel, J. S.  Induced-Fit Catalysis of Corannulene Bowl-to-Bowl Inversion.  Nature Chem. 2014, 6, 222‒228.

Barnes, J. C.; Juríček, M.; Vermeulen, N. A.; Dale, E. J.; Stoddart, J. F. Synthesis of ExnBox Cyclophanes.  J. Org. Chem. 2013, 78, 11962–11969.

Juríček, M. †; Barnes, J. C.†; Dale, E. J.; Liu, W.-G.; Strutt, N. L.; Bruns, C. J.; Vermeulen, N. A.; Ghooray, K.; Sarjeant, A. A.; Stern, C. L.; Botros, Y. Y.; Goddard, W. A., III; Stoddart, J. F.  Ex2Box: Interdependent Modes of Binding in a Two-Nanometer-Long Synthetic Receptor.  J. Am. Chem. Soc. 2013, 135, 12736–12746. †These authors contributed equally.

Barnes, J. C.; Fahrenbach, A. C.;  Cao, D.;  Dyar, S. M.;  Frasconi, M.; Giesener,  M. A.; Benítez, D.; Tkatchouk, E.; Chernyashevskyy, O.; Shin, W. H.; Li, H.; Sampath, S.; Stern, C. L.; Sarjeant, A. A.; Hartlieb, K. J.; Liu, Z.; Carmieli, R.; Botros, Y. Y.; Choi, J. W.; Slawin, A. M. Z.; Ketterson, J. B.; Wasielewski, M. R.; Goddard, W. A., III; Stoddart, J. F.  A Radically Configurable Six-State Compound.  Science  2013, 339, 429–433.  Highlighted in C&EN ‘News of the Week’, RSC’s Chemistry World, Nature Middle East, and Nature Chemistry’s News and Views.

Barnes, J. C.; Juríček, M.; Strutt, N. L.; Frasconi, M.; Sampath, S.; Giesener,  M. A.; McGrier, P. L.; Bruns, C. J.; Stern, C. L.; Sarjeant, A. A.; Stoddart, J. F.  ExBox: A Polycyclic Aromatic Hydrocarbon Scavenger. J. Am. Chem. Soc. 2013, 135, 183–192.  Front Cover Article. Highlighted in C&EN and RSC’s Chemistry World.

Barnes, J. C.; Fahrenbach, A. C.; Dyar, S. M.; Frasconi, M.; Giesener, M. A.; Zhu, Z.; Liu, Z.; Hartlieb, K. J.; Carmieli, R.; Wasielewski, M. R.; Stoddart, J. F.  Mechanically-Induced Intramolecular Electron Transfer in a Mixed-Valence Molecular Shuttle.  Proc. Natl. Acad. Sci. 2012, 109, 11546–11551.  Front Cover Article.

Fahrenbach, A. C.; Barnes, J. C.; Lanfranchi, D. A.; Li, H.; Coskun, A.; Gassensmith, J. J.; Liu, Z.; Benítez, D.; Trabolsi, A.; Goddard, W. A., III; Elhabiri, M.; Stoddart, J. F.  Solution-Phase Mechanistic Study and Solid-State Structure of a Tris(Bipyridinium Radical Cation) Inclusion Complex.  J. Am. Chem. Soc. 2012, 134, 3061–3072.

Li, Z.; Barnes, J. C.; Bosoy, A.; Stoddart, J. F.; Zink, J. I.  Mesoporous Silica Nanoparticles for Biomedical Applications.  Chem. Soc. Rev. 2012, 41, 2590–2605. 

 

Patents

Johnson, J. A.; Longyan, L.; Barnes, J. C. U.S. Provisional Patent Application 62/346,923.  Drug Delivery Polymers and Uses Thereof.  Filed: June 7, 2016.

Johnson, J. A.; Barnes, J. C.; Ehrlich, D. J. C.; Jiang, Y.; Gao, A. X. U.S. Patent Application 15/074,779.  Formation of Macromolecules Using Iterative Growth and Related Compounds.  Filed: June 6, 2016.

Stoddart, J. F.; Barnes, J. C.; Juricek, M.  U.S. Patent 9,290,495.  Tetracationic Cyclophanes and Their Use in the Sequestration of Polyaromatic Hydrocarbons By Way of Complexation.  Published: March 22, 2016.

Stoddart, J. F.; Dale, E. J.; Vermeulen, N. A.; Barnes, J. C.; Juricek, M.  U.S. Patent Application 14/844,577. ExCage: Synthesis of Viologen-Like Pyridinium-Based Cages for the Selective Capture of Polycyclic Aromatic Hydrocarbons.  Filed: September 3, 2015.    

Stoddart, J. F.; Fahrenbach, A. C.; Barnes, J. C.; Li, H.; Sampath, S.; Basuray, A.  U.S. Patent 9,120,799.  Crystalline Bipyridinium Radical Complexes and Uses Thereof.  Published: September 1, 2015.

Primary Faculty
  • Primary Faculty
  • Joint Faculty
  • Education Faculty/Staff
  • Research Faculty
  • Adjunct/Visiting Faculty
  • Emeritus Faculty
  • Executive Faculty
  • Research Staff
  • Administrative Staff
  • Join our Faculty
  • Faculty & Staff Directory
  • Postdoc Directory
  • Graduate Student Directory
  • Diversity Resources
  • News
  • Contact Us
  • Site Map

Department of Chemistry | (314) 935-6530 | chemistry@wustl.edu
Washington University in St. Louis | Campus Box 1134 | One Brookings Drive | St. Louis, MO 63130-4899